Which phase of the cardiac action potential corresponds to the plateau period?

Prepare for the Electrophysiology Unit (EPU) 26.19 exam with our interactive quiz featuring flashcards and multiple choice questions. Check your understanding with hints and explanations for each question.

Multiple Choice

Which phase of the cardiac action potential corresponds to the plateau period?

Explanation:
The plateau period is the phase where the inward calcium current balances the outward potassium current, keeping the cell membrane depolarized for an extended time. As L-type calcium channels open, Ca2+ enters the cell and sustains depolarization, so the membrane potential stays around a depolarized level for several hundred milliseconds. This prolonged depolarization also triggers calcium-induced calcium release for contraction, linking electrical activity to force generation. In contrast, the rapid upstroke phase is driven mainly by a quick sodium influx that rapidly depolarizes the cell; the early transient outward current causes a brief notch after the upstroke; and the final repolarization phase is when potassium efflux dominates, returning the membrane to its resting potential.

The plateau period is the phase where the inward calcium current balances the outward potassium current, keeping the cell membrane depolarized for an extended time. As L-type calcium channels open, Ca2+ enters the cell and sustains depolarization, so the membrane potential stays around a depolarized level for several hundred milliseconds. This prolonged depolarization also triggers calcium-induced calcium release for contraction, linking electrical activity to force generation.

In contrast, the rapid upstroke phase is driven mainly by a quick sodium influx that rapidly depolarizes the cell; the early transient outward current causes a brief notch after the upstroke; and the final repolarization phase is when potassium efflux dominates, returning the membrane to its resting potential.

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